Pierre Nottelet

Research

My research focuses on advancing the understanding of cell-matrix interactions at the molecular level through the development of a pioneering workflow that combines 3D bioprinted matrices and Cryo-Electron Tomography (CryoET). This innovative approach enables the detailed visualization of cell matrix interactions within their inherent 3D milieu, thereby presenting revolutionary perspectives for cell biology, tissue engineering, and regenerative medicine.

Education

• 2018-2022: Ph.D. in structural biology – European Institute of Chemistry and Biology (IECB), Structure & function of bacterial nanomachines, UMR 5234, Bordeaux, France
• 2016-2018: Master in organic chemistry and life science – University of Bordeaux, France
• 2013-2016: Bachelor’s degree in chemistry – University of Bordeaux, France

Experience

• 2018-2022: Thesis at the European Institute of Chemistry and Biology (IECB) (Bordeaux) UMR 5234, MFP Supervisor: Dr. R. FRONZES Project: Structural characterization of a bacterial antibody-degrading system.
• 2018 (5 months): Internship at the IECB (Bordeaux) INSERM U1212 Supervisor: Dr. G. SALGADO Project: In vitro and in vivo study of C9orf72 RNA G-quadruplex, proteins and ligands that target this structure.
• 2017 (2 months): Internship at the IECB (Bordeaux) INSERM U1212 Supervisor: Dr. G. SALGADO Project: in vitro and in vivo study of KRAS oncogene G-quadruplex structure and its interaction with little ligands.
• 2016 (1 month): Internship at the IECB (Bordeaux) INSERM U1212 Supervisor: Dr. G. SALGADO Project: KRAS oncogene G-quadruplex structure and its interaction with little ligands.